支障

大雪のため、交通に大きな支障が出ている。

The heavy snow is causing major disruption to traffic.

睡眠不足が続くと、仕事に支障をきたす。

If you keep getting too little sleep, it will interfere with your work.

日常生活に支障のない程度の軽いけがで済んだ。

The injury was minor enough not to affect his daily life.