Computational Chemist, Senior Principal Scientist

We’re seeking a Computational Chemist to join us in our mission to transform the discovery of therapeutics and materials!

Our drug discovery group of over 60 scientists includes designers, modelers, computational chemists, medicinal chemists, crystallographers, biochemists, and biologists with experience working on all common target classes and therapeutic areas. The group is supported by more than 100 software developers and engineers, as well as a large scale computer infrastructure. Four of the programs we’ve worked on in the past seven years have progressed into the clinic; two are still progressing through trials and two have been approved by the FDA.

This employee will be hired at the Senior Principal Scientist level.

Who will love this job

• An experienced drug designer with a proven track record of utilizing state-of-the-art computational models to advance drug discovery projects
• A modeler with demonstrated expertise in two or more of the following molecular modeling areas: virtual ligand screening, computationally-driven lead optimization, AI/machine learning, molecular dynamics, quantum mechanics, cheminformatics, ADMET/QSPR
• An excellent communicator with experience in one or more other disciplines of relevance to drug discovery, such as synthetic organic chemistry, pharmacology, toxicology, formulation, biochemistry, physical chemistry, or analytical chemistry
• A team player who enjoys working in interdisciplinary environments and has some background in programming/scripting and/or chemically-aware databases
• A pharma/biotech expert

What you’ll do

• Support active drug discovery projects as a lead computational chemist/modeler
• Develop modeling strategy for drug discovery projects, and take ownership of execution
• Collaborate across global, cross-functional teams in multiple languages, accounting for differences in time zone and work culture
• Prepare and present project updates to senior leadership, collaborators and partners
• Provide guidance and mentorship to junior team members
• Work closely with internal software development teams to improve our drug discovery technologies

What you should have

• PhD in computational chemistry, organic chemistry, or physical chemistry
• At least eight years of industry experience
• Fluency in Japanese, business level proficiency in English

Pay and Perks:
Schrödinger understands that it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, bonus plan, and benefits, which includes mutual-aid retirement plans, over three weeks of paid vacation time, numerous company holidays, a parental and family care leave program, and healthcare through our partnership with the Japanese Health Insurance Association, and professional development opportunities including trainings and continuous education support.