この町は時代の転変とともに姿を変えてきた。
This town has changed its appearance along with the changes of the times.
彼は世の転変の激しさを身をもって知った。
He learned firsthand how violently the world can change.
祖母は戦後の転変を生き抜いてきた人だ。
My grandmother is someone who lived through the upheavals of the postwar years.
人の運命の転変は誰にも予測できない。
No one can predict the vicissitudes of a person's fate.